Herpes simplex
☆ Nos resultados do Stiftung Warentest de 2022 da Alemanha, a satisfação do consumidor com o ModelDerm foi apenas ligeiramente inferior do que com as consultas pagas de telemedicina.
Herpes simples no lábio.
Herpes simplex ― A infecção por herpes simplex nos dedos é mais comum em crianças pequenas do que em adultos.
References
A infecção pelo HSV-1 progride através da infecção primária das células epiteliais, seguida de latência, principalmente nos neurônios, e reativação. O HSV-1 comumente causa erupções vesiculares iniciais e recorrentes, principalmente na boca e na mucosa genital. Suas manifestações variam desde herpes orolabial até diversas condições como foliculite herpética, infecções de pele, envolvimento ocular e casos graves como encefalite herpética. A terapia antiviral ajuda a controlar a infecção por HSV.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 2 (HSV-2) é uma infecção generalizada, afetando cerca de 22% dos adultos com 12 anos ou mais, totalizando 45 milhões de adultos nos Estados Unidos. Embora o HSV-1 normalmente cause feridas orais, também pode causar lesões genitais. No entanto, quando os pacientes apresentam lesões genitais, o HSV-2 costuma ser a principal preocupação. Os sintomas dos surtos de HSV-2 são frequentemente vagos, como coceira e irritação genital, o que pode atrasar o diagnóstico e o tratamento. Este atraso pode resultar em transmissão adicional para indivíduos não infectados.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus (HSV) comumente causa infecções como herpes genital e herpes labial em adolescentes e adultos. Quando o HSV infecta uma criança nas primeiras 4-6 semanas de vida, pode resultar em doença grave com consequências graves. Diagnosticar rapidamente a infecção neonatal por HSV é crucial para impedir o agravamento da doença, prevenindo problemas neurológicos (até mesmo a morte) .
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex A infecção é muito comum e pode ser transmitida de mulheres grávidas para seus bebês. Este vírus pode causar sérios problemas de saúde ou até a morte de recém-nascidos. Embora seja raro durante a gravidez, geralmente acontece durante o parto. O risco é maior se a mãe for infectada nas fases posteriores da gravidez. Porém, esse risco pode ser reduzido com o uso de medicamentos antivirais ou optando pela cesariana em determinadas situações.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Herpes simplex virus (HSV) os tipos 1 e 2 infectam muitas pessoas em todo o mundo. Normalmente, o vírus permanece quieto nas células nervosas após infectar a pele, mas pode ser reativado mais tarde, causando herpes labial. Às vezes, leva a problemas graves, como infecções oculares, inflamação cerebral ou condições perigosas em recém-nascidos e pessoas com sistema imunológico fraco. Embora os medicamentos atuais ajudem a controlar as infeções, o risco de resistência aos medicamentos e de efeitos secundários continua a ser uma preocupação. Precisamos de novos medicamentos para combater melhor o vírus.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Existem dois tipos de vírus herpes simplex , tipo 1 (HSV-1) e tipo 2 (HSV-2). O HSV-1 causa mais comumente infecções ao redor da boca, enquanto o HSV-2 causa mais comumente infecções genitais. São transmitidos por contato direto com o indivíduo infectado. O herpes genital é classificado como uma infecção sexualmente transmissível. Pode ser transmitido a uma criança durante o parto. Após a infecção, os vírus são transportados ao longo dos nervos sensoriais até os corpos das células nervosas, onde residem por toda a vida. As causas de recorrência podem incluir: diminuição da função imunológica, estresse e exposição à luz solar.
Na maioria dos casos, os medicamentos antivirais são tomados apenas quando os sintomas são graves. Medicamentos antivirais diários podem ser prescritos para alguém que tem infecções muito frequentes. Não há vacina disponível e a vacina contra herpes zoster não previne o herpes simples. Os tratamentos com medicamentos antivirais como aciclovir ou valaciclovir podem diminuir a gravidade dos sintomas.
As taxas mundiais de HSV-1 ou HSV-2 estão entre 60% e 95% em adultos. O HSV-1 geralmente é infectado durante a infância. Estima-se que 536 milhões de pessoas em todo o mundo (16% da população) foram infectadas pelo HSV-2 em 2003, com taxas mais elevadas entre as mulheres e as do mundo em desenvolvimento. A maioria das pessoas com HSV-2 não percebe que está infectada.
○ Tratamento - Medicamentos OTC
Evite qualquer contato físico, como beijar uma criança, enquanto as bolhas estiverem presentes, pois o contato pode espalhar a infecção para outras pessoas. Você deve descansar sem beber álcool.
#Acyclovir cream